【关注度高】柳氮磺吡啶对溃疡性结肠炎有着较好的疗效

Mainly used to treat ulcerative colitis and non-specific colitis. Sulfasalazine has a good effect on ulcerative colitis. It can treat mild to moderate ulcerative colitis and can also be used as an auxiliary treatment for severe ulcerative colitis.

Ulcerative colitis is a chronic non-specific inflammatory disease of the colon and rectum whose cause is not yet fully understood. The clinical manifestations of ulcerative colitis include diarrhea, abdominal pain, mucus and purulent and bloody stools, constipation, and inability to pass stool within a few days. The incidence of ulcerative colitis in my country is gradually increasing. Sulfasalazine (Xinyi) has brought new treatment options to patients with ulcerative colitis.

A clinical trial was conducted to compare and observe the clinical efficacy of mesalazine and sulfasalazine (Xinyi) in the treatment of ulcerative colitis. Experimental method: 90 patients with ulcerative colitis were randomly divided into a treatment group and a control group, with 40 cases in each group. The treatment group was treated with mesalazine, and the control group was treated with sulfasalazine. The treatment course of the patients was 8 weeks. Observe and compare the efficacy and occurrence of adverse reactions between the treatment group and the control group. Results: In the treatment group, 32 cases were markedly effective, 89 cases were effective, and 4 cases were ineffective, with a total effective rate of 91.1%; in the control group, 22 cases were markedly effective, 11 cases were effective, and 12 cases were ineffective, with a total effective rate of 73.3%. The total effective rate in the treatment group was significantly higher than that in the control group (P<0.05). Conclusion: Sulfasalazine (Xinyi) has mild adverse reactions and good efficacy in the treatment of ulcerative colitis.

Sulfasalazine (Xinyi) has been associated with anti-inflammatory and immunomodulatory effects in animal and in vitro experiments. Animal autoradiography studies have shown that sulfasalazine (SSZ) has an affinity for connective tissue and is present at relatively high levels in the serous fluid, liver and intestinal wall. For more drug consultation on Sulfasalazine (Xinyi), patients can contact the customer service of the domestic overseas medical service institution Medical Companion Travel for detailed information.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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