意美用法用量

Yimei is the first neurokinin-1 (NK-1) receptor blocker approved by the US FDA in 2003. Blocks the effects of substance P by binding to NK-1 receptors (mainly found in the central nervous system and its periphery). It can pass through the blood-brain barrier and occupy the NK-1 receptor in the brain. It has selectivity and high affinity and has low affinity for NK-2 and NK-3 receptors. Its effect in reducing nausea and vomiting is better than other drugs.

The antiemetic mechanism of Yimei is: Yimei can bind to neurokinin-1 receptors, block substance P, and improve symptoms of nausea and vomiting. Yimei also has a high binding rate to protein. Combining the drug with other antiemetics can improve the antiemetic effect and improve the patient's treatment compliance.

Yimeide Dosage: Yimeide is a three-day intervention and includes a course of treatment with a corticosteroid and a 5-HT3 antagonist. The recommended dose of Yimei is 125 mg taken orally one hour before chemotherapy on the first day, and 80 mg once daily in the morning on the second and third days.

Yimei can be taken with or without food. Applicable and contraindication groups for taking the medicine: 1. Suitable population: patients with vomiting symptoms during chemotherapy; 2. Contraindicated groups, those allergic to any component of Yimei capsules; patients taking pimozide, terfenadine, astemizole and other drugs. 3. Pregnant women, the elderly, and children are not allowed to take this medicine. Pregnant women and lactating women are not allowed to take this medicine. The safety of this medicine is unknown for children, so it should be used with caution. There are no clear contraindications for the elderly.

It was officially approved for sale in China on August 22, 2014, and has also been included in the national medical insurance to provide everyone with government discounts to reduce the financial burden. The specifications of Yimei capsules after medical insurance are 3 capsules per box (0.125gx1 capsule + 80mgx2 capsules). The price of each box is about $600, which is still relatively high. According to Medical Companion Travel, we learned that the price of Yimei is about 60$, which is more suitable for patients to use for a long time. It is cheaper and more cost-effective. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about Yimei, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.