今天给大家谈谈使用阿瑞匹坦时需要注意的事

The FDA approved aprepitant in 2003 along with standard antiemetic regimens for the prevention and treatment of chemotherapy-associated nausea and vomiting (CINV). Patients may benefit from the addition of antiemetic agents to highly emetogenic chemotherapy regimens for various hematological malignancies. Before autologous hematopoietic stem cell transplantation (auto-HSCT), large doses of busulfan, cytarabine, melphalan, cyclophosphamide and other moderately and highly emetogenic drugs are used as pretreatment, and the use of aprepitant is more likely to benefit patients clinically. The use of aprepitant to antiemetic has been reported in patients with hematopoietic stem cell transplantation. Aprepitant can increase the antiemetic effect but does not increase transplantation-related toxic side effects. Today, the editor will talk to you about things you need to pay attention to when using aprepitant.

: During pregnancy, aprepitant should be used only when the potential benefits outweigh the possible risks to the mother and woman. Aprepitant may induce adverse reactions in infants who drink breast milk, so the nature of this drug to the mother must be considered and a choice should be made between stopping breastfeeding or discontinuing the drug. The efficacy of oral contraceptives may be reduced during long-term use of aprepitant.

Symptoms include: pelvic pain, bradycardia, hiccups, elevated liver index ALT, anorexia, disorientation, perforated duodenal ulcer, upper respiratory tract infection, tachycardia, constipation, headache, skeletal pain, rash, hypokalemia, redness, fatigue, weakness, pain, anxiety, weakness, Stevens-Johnson syndrome, etc. Here, the editor solemnly wants to tell all patients who are taking aprepitant. It is recommended that you take the medication correctly according to the doctor's instructions during the medication. Do not listen to others who say that doubling the dose of the drug can improve the therapeutic effect, and do not believe in rumors that lowering the dose can reduce side effects. Only by strictly following the doctor's instructions can you achieve the best effect on your own treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.