阿瑞匹坦应该如何使用？长期用阿瑞匹坦会有哪些副作用

Aprepitant is a selective and high-affinity antagonist. Preclinical studies have shown that the drug can penetrate into the brain and bind to the brain's NK1 receptor. Aprepitant has a long-lasting effect on the central system and can inhibit cisplatin-induced vomiting in the acute and delayed phases. How should it be used? What are the side effects of long-term use of aprepitant?

How to use aprepitant

Aprepitant is a three-day intervention and includes a course of treatment with a corticosteroid and a 5-HT3 antagonist.

The recommended dose of Aprepitant is 125 mg taken orally one hour before chemotherapy on the first day, and 80 mg once daily in the morning on the second and third days. During Aprepitant treatment, patients should strictly follow the doctor's diagnosis and treatment recommendations and should not increase or decrease the dosage without authorization to avoid other adverse reactions caused by incorrect medication and delay the condition.

Aprepitant side effects

The side effects of aprepitant include: hiccups, weakness, fatigue, elevated liver index ALT, constipation, headache, anorexia, red complexion, upper respiratory tract infection, tachycardia, pelvic pain, bone pain, rash, hypokalemia, anxiety, perforated duodenal ulcer, etc. Since each patient's disease progression and tolerance to drugs are different, the side effects, severity, and number of side effects after receiving aprepitant treatment will also be different. If patients feel unwell during Aprepitant treatment, they must go to the hospital for treatment, and a professional doctor will diagnose whether the patient needs to continue taking the medication. Patients are not allowed to use this medicine for treatment without authorization and must take it according to the doctor's instructions.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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