埃索美拉唑是用来治什么的？

It is suitable for the treatment of gastroesophageal reflux disease, reflux esophagitis, long-term treatment to prevent recurrence of cured esophagitis patients, and the eradication of Helicobacter pylori in combination with appropriate antibiotics. Swallow the esomeprazole tablet whole with warm water; do not chew or crush it. For patients with dysphagia, drink boiled water until the tablet is completely disintegrated and take it within 30 minutes. The adverse reactions of esomeprazole are nervous headache, diarrhea, nausea, flatulence, etc.

Experience with overdose of this product is very limited. After the patient took 280 mg of esomeprazole orally, the main symptoms were gastrointestinal symptoms and weakness. The patient had no abnormal reactions after a single oral dose of 80 mg esomeprazole and intravenous esomeprazole 308 mg within 24 hours. There is no known specific antidote for esomeprazole. Esomeprazole is extensively bound to plasma proteins and therefore difficult to dialyze. Treatment of any overdose-induced poisoning should be symptomatic and systemic supportive therapy.

In routine single- and multiple-dose toxicity studies, teratogenicity, mutagenicity and other preclinical-related experimental studies, there is no evidence that esomeprazole has special hazards to humans. Carcinogenicity studies of oral administration of a racemic mixture (omeprazole) in rats identified gastric enterochromaffin-like (ECL) cell hyperplasia and carcinoid tumors. These effects are secondary to the sustained reduction in gastric acid production and the marked hypergastrinemia seen in rats after chronic administration of gastric acid secretion inhibitors. Using any method, including proton pump inhibitors, to reduce the acidity of gastric juice will increase the number of bacteria in the stomach (usually found in the gastrointestinal tract). Treatment with proton pump inhibitors may result in a slightly increased risk of gastrointestinal infections (such as Salmonella and Campylobacter).

The safety and effectiveness of esomeprazole treatment have been verified in two trials: a clinical comparative study of esomeprazole and omeprazole in the treatment of reflux esophagitis. The total effective rate of esomeprazole was 97.18%, which was significantly higher than that of omeprazole, which was 84.51%. There was no significant difference in the incidence of adverse reactions.

The above are the diseases that can be treated by our Medical Companion Travel Overseas Medical Consulting Service Company. If the patient has other questions, please consult the Medical Companion Travel Service.