埃索美拉唑2020年价格

Esomeprazole (Nexium) is the S-optical isomer of omeprazole and the world's first isomer proton pump inhibitor (PPI). It reduces gastric acid secretion by specifically inhibiting the proton pump of gastric parietal cells. It has been confirmed by a large number of clinical experiments and drug research: it can maintain gastric pH>4 for a longer time, has higher acid suppression efficiency, and is more effective than the previous two generations of PPI, with small individual differences. As a new generation of PPI, it has been widely used in clinical treatment of many acid-related diseases. Esomeprazole, trade name Nexium, is a single isomer of omeprazole, the (S)-isomer. Due to its metabolic advantages, esomeprazole has higher bioavailability and more consistent pharmacokinetics than omeprazole, which increases the amount of drugs reaching the proton pump and has a better acid-suppressing effect than other PPIs.

The approved indication of esomeprazole (Nexium) is to prevent the recurrence of gastric ulcer and duodenal ulcer in patients receiving nonsteroidal anti-inflammatory drugs (NSAIDs). The approved indications of esomeprazole in Japan include reflux esophagitis and non-erosive reflux disease (NERD).

What is the price of esomeprazole in 2020?

Medical Travel learned that the Indian version of esomeprazole (Nexium) is the cheapest, with a box costing about 500.

In clinical trials, a clinical comparative study of esomeprazole (Nexium) and omeprazole in the treatment of reflux esophagitis showed that the total effective rate of esomeprazole was 97.18%, which was significantly higher than 84.51% of omeprazole, and there was no significant difference in the incidence of adverse reactions. Chen Caiming has done a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than 78.6% for omeprazole. The results proved that esomeprazole has a cost-effectiveness advantage.