埃索美拉唑的价格

Price of esomeprazole: Medical Companion Travel learned that the price of the Japanese version of esomeprazole (Nexium) is about 1,900, and the Indian version is about 500.

Esomeprazole (Nexium) magnesium enteric-coated tablets are mainly suitable for the treatment of gastroesophageal reflux disease (GERD) - erosive reflux esophagitis. Long-term maintenance treatment to prevent recurrence in patients with cured esophagitis. Symptom control of gastroesophageal reflux disease (GERD). Used in combination with appropriate antimicrobial therapy to eradicate Helicobacter pylori and - to heal duodenal ulcers associated with Helicobacter pylori infection - to prevent the recurrence of peptic ulcers associated with Helicobacter pylori infection.

Esomeprazole (Nexium) is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. Site and mechanism of action: Esomeprazole is a weak base, which is concentrated in the high-acid environment of parietal cell acid secretion microtubules and converted into an active form, thereby inhibiting the H+/K+-ATPase (proton pump) at this site, inhibiting both basic gastric acid secretion and stimulated gastric acid secretion. Effect on gastric acid secretion After oral administration of 20 mg and 40 mg of esomeprazole, it takes effect within one hour. Repeat administration of 20 mg once a day for 5 consecutive times, and measure 6-7 hours after taking the drug on the fifth day. The average peak acid secretion caused by pentagastrin stimulation is reduced by 90%.

The chemical name of esomeprazole is S-5-methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl}-1H-benzimidazole. On July 30, 2020, AstraZeneca announced that the China National Medical Products Administration (NMPA) officially approved Nexium (esomeprazole sodium) injection for the prevention of stress ulcer bleeding in severe patients.