埃索美拉唑和雷贝拉唑哪个效果好

The active ingredient in (Nexium) magnesium enteric-coated tablets is esomeprazole magnesium. Esomeprazole is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. Rabeprazole sodium enteric-coated capsules are also suitable for digestive diseases. So, which one is better, esomeprazole (Nexium) or rabeprazole?

Esomeprazole (Nexium) magnesium enteric-coated tablets are suitable for the treatment of gastroesophageal reflux disease (GERD), erosive reflux esophagitis, and long-term maintenance treatment to prevent recurrence of cured esophagitis patients.

The main component of rabeprazole sodium enteric-coated capsules is rabeprazole sodium. Rabeprazole is a benzimidazole compound and a second-generation proton pump inhibitor. It blocks the final step of gastric acid secretion by specifically inhibiting the H+-K+ ATPase system of gastric parietal cells. This effect is dose-dependent and can inhibit both basal gastric acid secretion and gastric acid secretion under stimulation. This product has no antagonistic effect on choline and histamine H2 receptors.

To observe the clinical efficacy of a 2-week course of esomeprazole (Nexium) triple combination and rabeprazole triple combination in the eradication of Helicobacter pylori infection. Methods: Patients with Helicobacter pylori infection who were both positive in the C14 urea breath test and the rapid urease test of gastric mucosal biopsy under gastroscopy were selected. According to the different proton pump inhibitors (PPI) used, they were divided into the esomeprazole group and the rabeprazole group, and the different PPIs were compared. The eradication rate of Helicobacter pylori by triple 2-week treatment.

Results: The eradication rate of the esomeprazole (Nexium) group was 95.8%, and the eradication rate of the rabeprazole group was 74.4%. Compared with the two groups, the difference was statistically significant (P <0.05). Conclusion Esomeprazole triple 2-week therapy is safe and effective in the treatment of Hp-positive patients, and the difference is statistically significant compared with the rabeprazole group. It is recommended that areas with good economic conditions can be used as the first choice treatment option.

Compare the efficacy of esomeprazole (Nexium) quadruple therapy and rabeprazole quadruple therapy in eradicating Helicobacter pylori. Methods: 148 HP-positive patients admitted to our hospital were randomly divided into esomeprazole quadruple therapy group and rabeprazole quadruple therapy group. After 14 days of corresponding treatment, the Hp eradication was detected after 4 weeks of drug withdrawal. Rate. Results: The HP eradication rate in the esomeprazole quadruple therapy group was 91.8%, and the HP eradication rate in the bismuth quadruple therapy group was 73.0%. The difference in Hp eradication rates between the two groups was statistically significant (P<0.05). Conclusion: The anti-HP efficacy of esomeprazole quadruple therapy is better than that of rabeprazole quadruple therapy, and it is worthy of promotion.

The above is the content of the effects of (Nexium) and rabeprazole, I hope it can help you!

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