日本版的埃索美拉唑多少钱

The plasma protein binding rate of (Nexium) is 97%. Eating food will delay and reduce the absorption of esomeprazole, but has no significant effect on the effect of esomeprazole on reducing gastric acidity. Metabolism and Excretion Esomeprazole is completely metabolized by the cytochrome P450 enzyme system (CYP). Most of the metabolism of esomeprazole relies on polymorphic CYP2C19, resulting in the hydroxylate and demethyl metabolites of esomeprazole (Nexium). Today let’s take a closer look at how much does the Japanese version of esomeprazole cost?

According to the Medical Companion Brigade, the Japanese version of esomeprazole (Nexium) costs around 1,900, and the Indian version costs around 500. Since exchange rates fluctuate and prices are not fixed, please consult Medical Travel for specific prices. Patients can choose domestic professional overseas medical service institutions (such as Medical Companion Travel) to purchase through direct mail. You can also buy esomeprazole abroad.

Esomeprazole (Nexium) is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. The R-isomer and S-isomer of omeprazole have similar pharmacodynamic properties. The site and mechanism of action. Esomeprazole is a weak base, which is concentrated in the high-acid environment of the acid secretion microtubules of parietal cells and converted into an active form, thereby inhibiting the H+/K+-ATPase (proton pump) at this site, inhibiting both basal gastric acid secretion and stimulated gastric acid secretion.

How to take esomeprazole (Nexium): 1. The tablet should be swallowed whole with liquid and should not be chewed or crushed. 2. For patients with dysphagia, the tablets can be dissolved in half a cup of carbonate-free water (other liquids should not be used as the enteric coating may be dissolved), stir until the tablets are completely disintegrated, take it immediately or within 30 minutes, then add half a cup of water to rinse and drink. Pellets should never be chewed or crushed. 3. For patients who cannot swallow, the tablets can be dissolved in carbonate-free water and administered through a gastric tube.

Esomeprazole (Nexium) can inhibit gastric acid secretion through specific targeting, and its bioavailability and achievable blood concentration are both high. Esomeprazole's continuous inhibition time of gastric acid and the time it takes to maintain the gastric pH value greater than 4 (the larger the pH value, the weaker the acidity) are longer than other acid suppressants.

The above is the price content of (Nexium), I hope it can help you!

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