埃索美拉唑好不好

(Nexium) is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. Esomeprazole magnesium enteric-coated tablets are suitable for the treatment of gastroesophageal reflux disease (GERD), erosive reflux esophagitis, and long-term maintenance treatment to prevent recurrence of cured esophagitis patients. Today let’s take a closer look at the Indian version of esomeprazole, is it good?

In a clinical comparative study of esomeprazole (Nexium) and omeprazole in the treatment of reflux esophagitis, the total effective rate of esomeprazole was 97.18%, which was significantly higher than 84.51% of omeprazole, and there was no significant difference in the incidence of adverse reactions. Chen Caiming conducted a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than that of omeprazole, 78.6%. The results proved that esomeprazole has cost and effectiveness advantages.

80 patients with gastroesophageal reflux disease were treated from January 2011 to December 2013 and were randomly divided into two groups, 40 cases in each group. The observation group was treated with standard dose esomeprazole (Nexium), and the control group was treated with high-dose omeprazole. Both groups were treated for 8 weeks. The relief of symptoms such as heartburn, acid reflux, chest pain, and dysphagia were observed before and after treatment, and the changes in symptom scores were counted.

The SF-36 health scale was used to evaluate the changes in patients' quality of life before and after treatment. SPSS 19.0 statistical software was used for data processing. Count data were expressed as percentages. Comparisons between groups used χ2 tests. Measurement data were expressed as (xˉ±s). Comparisons between groups used independent sample t tests. Comparisons within groups before and after treatment used paired t tests. P0.05). The heartburn and chest pain relief rates of the observation group were higher than those of the control group (both P0.05).

After treatment, the physical pain, overall health, vitality, social function, emotional function and mental health of both groups were improved compared with before treatment (all P<0.05); the physical pain, vitality and social function scores of the observation group were significantly higher than those of the control group (all P<0.05). Conclusion Compared with high-dose omeprazole, conventional dose esomeprazole (Nexium) can more effectively relieve the clinical symptoms of patients with gastroesophageal reflux. In addition, it has obvious advantages in improving patients' quality of life and is worthy of application.

The above is the content of (Nexium) effect, I hope it can help you!

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