耐信每天什么时候吃？

In a clinical comparative study between (esomeprazole) and omeprazole in the treatment of reflux esophagitis, Nexium's total effective rate was 97.18%, which was significantly higher than omeprazole's 84.51%, and there was no significant difference in the incidence of adverse reactions. Today let’s take a closer look at when to take Nexium every day?

1. Treatment of erosive reflux esophagitis: Nexium (esomeprazole) 40 mg once a day for 4 weeks. For patients whose esophagitis is not cured or whose symptoms persist, a further 4 weeks of treatment is recommended.

2. Long-term maintenance treatment for cured esophagitis patients to prevent recurrence: 20 mg once a day.

3. Symptom control of GERD (gastroesophageal reflux disease): patients without esophagitis take 20 mg once a day. If symptoms are not controlled after 4 weeks of medication, the patient should undergo further examination. After the symptoms disappear, immediate therapy can be used (ie, 20 mg orally, once a day if necessary).

4. Combined antimicrobial therapy to eradicate Helicobacter pylori: Use a combined medication regimen of 20 mg of this drug once, 1 g of amoxicillin once, and 500 mg of clarithromycin once, twice a day for 7 days.

Tablets should be swallowed whole with liquid and should not be chewed or crushed.

For patients with difficulty swallowing, put it into boiled water until the tablet is completely disintegrated and take it within 30 minutes.

Experience with overdose with Nexium (esomeprazole) is very limited. After the patient took Nexium 280 mg orally, the main symptoms were gastrointestinal symptoms and weakness. The patient had no abnormal reactions after taking a single oral dose of Nexium 80 mg and intravenous administration of Nexium 308 mg within 24 hours.

There is no known specific antidote for Nexium (esomeprazole). Nexium is extensively bound to plasma proteins and therefore difficult to dialyze. Treatment of any overdose-induced poisoning should be symptomatic and systemic supportive therapy.

Nexium is a proton pump inhibitor that inhibits gastric acid secretion by specifically inhibiting H+/K+-ATPase in gastric parietal cells. The S- and R-isomers of omeprazole are protonated and converted in the acidic compartment of the parietal cell to form the active inhibitor achiral sulfonamide. By acting specifically on the proton pump, Nexium blocks the final steps in acid production, thereby reducing gastric acidity.

The above is the content of how to take (esomeprazole), I hope it can help you!

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