耐信一天服用多少剂量?
(Esomeprazole) causes gastric pH to remain >4 for a longer period of time. A study on the duration of gastric pH > 4 and the healing rate of reflux esophagitis showed that the longer the duration of pH > 4 within 24 hours, the greater the number of patients who healed after 8 weeks. After taking different drugs orally for 5 days, the duration of pH>4 in the stomach within 24 hours from longest to shortest is: Nexium 40mg, omeprazole 40mg, lansoprazole 30mg, pantoprazole 40mg and rabeprazole 20mg. This shows that Nexium 40mg has a stronger acid-suppressing effect than other proton pump inhibitors. Today we will take a closer look at how much dosage of Nexium should be taken in a day?
1. Treatment of erosive reflux esophagitis: 40 mg once a day for 4 weeks. For patients whose esophagitis is not cured or whose symptoms persist, a further 4 weeks of treatment is recommended. 2. Long-term maintenance treatment for cured esophagitis patients to prevent recurrence: Nexium (esomeprazole) 20 mg once a day. 3. Symptom control of GERD (gastroesophageal reflux disease): patients without esophagitis take 20 mg once a day. If symptoms are not controlled after 4 weeks of medication, the patient should undergo further examination. After the symptoms disappear, immediate therapy can be used (ie, 20 mg orally, once a day if necessary).
4. Combined antimicrobial therapy to eradicate Helicobacter pylori: Use a combined medication regimen, including Nexium (esomeprazole) 20 mg once, amoxicillin 1g once, and clarithromycin 500mg once, all twice a day for 7 days. Tablets should be swallowed whole with liquid and should not be chewed or crushed. For patients with difficulty swallowing, put it into boiled water until the tablet is completely disintegrated and take it within 30 minutes.
Nexium (esomeprazole) for injection:
1. The drip solution is prepared by dissolving 1 vial of Nexium into 100ml of 0.9% sodium chloride solution for intravenous drip use.
2. The prepared injection or infusion liquid is a colorless to very slightly yellow clear solution, which should be used within 12 hours and stored below 30°C.
3. From a microbiological point of view, it is best to use it immediately.
4. Incompatibility The degradation of the prepared solution is highly dependent on the pH value. The prepared solution should not be mixed with other drugs or used together in the same infusion device. Must be applied according to instructions for use. The intravenous injection time of the prepared solution should be at least 3 minutes. Infusion medication: The intravenous infusion time of the prepared solution should be within 30 minutes.
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