耐信什么时候吃？

(Esomeprazole) is indicated for: Gastroesophageal reflux disease (GERD): treatment of reflux esophagitis and long-term treatment to prevent recurrence in patients with cured esophagitis. Nexium can inhibit gastric acid secretion through specific targeting, and its bioavailability and achievable blood concentration are both high. On July 30, 2020, AstraZeneca announced that China’s National Medical Products Administration (NMPA) had officially approved Nexium injection for the prevention of stress ulcer bleeding in severe patients. Today we will learn more about when to take Nexium?

How to take Nexium (esomeprazole): 1. The tablet should be swallowed whole with liquid and should not be chewed or crushed. 2. For patients with dysphagia, the tablets can be dissolved in half a cup of carbonate-free water (other liquids should not be used as the enteric coating may be dissolved), stir until the tablets are completely disintegrated, take it immediately or within 30 minutes, then add half a cup of water to rinse and drink. Pellets should never be chewed or crushed. 3. For patients who cannot swallow, the tablets can be dissolved in carbonate-free water and administered through a gastric tube.

  The specific usage method is as follows:

1. Treatment of erosive reflux esophagitis: Nexium 40 mg once a day for 4 weeks. For patients whose esophagitis is not cured or whose symptoms persist, a further 4 weeks of treatment is recommended.

2. Long-term maintenance treatment for cured esophagitis patients to prevent recurrence: 20 mg once a day.

3. Symptom control of GERD (gastroesophageal reflux disease): patients without esophagitis take 20 mg once a day. If symptoms are not controlled after 4 weeks of medication, the patient should undergo further examination. After the symptoms disappear, immediate therapy can be used (ie, 20 mg orally, once a day if necessary).

4. Combined antimicrobial therapy to eradicate Helicobacter pylori: Use a combined medication regimen, including Nexium (esomeprazole) 20 mg once, amoxicillin 1g once, and clarithromycin 500mg once, all twice a day for 7 days.

Nexium (esomeprazole) is a specific inhibitor of proton pumps in gastric parietal cells. Nexium is the S-isomer of omeprazole, which reduces gastric acid secretion through specific proton pump inhibition. The R-isomer and S-isomer of omeprazole have similar pharmacodynamic properties. Nexium is a weakly alkaline drug that is concentrated in the high-acid environment of parietal cell acid secretion microtubules and converted into an active form, thereby inhibiting the H+/K+-ATPase (proton pump) at this site and inhibiting both basic gastric acid secretion and stimulated gastric acid secretion.

The above is the content of how to take (esomeprazole), I hope it can help you!

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