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埃索美拉唑治疗胃痛效果好吗

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

(Nexium, esomeprazole) is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. The R-isomer and S-isomer of omeprazole have similar pharmacodynamic properties. The site of action and mechanism of Nexium is a weak base, which is concentrated in the high-acid environment of the acid secretion microtubules of parietal cells and converted into an active form, thereby inhibiting the H+/K+-ATPase (proton pump) at this site and inhibiting both basal gastric acid secretion and stimulated gastric acid secretion.

Is esomeprazole effective in treating stomach pain?

The results of a randomized clinical trial using cimetidine as a positive control showed that during the treatment evaluation period, the esomeprazole (Nexium, esomeprazole) group had a lower upper gastrointestinal bleeding rate than the cimetidine group (2.7% in the esomeprazole group and 4.6% in the cimetidine group). Esomeprazole (Nexium, esomeprazole) 40 mg twice a day can effectively prevent upper gastrointestinal bleeding in severe patients. The safety profile of the esomeprazole (Nexium) group was similar to that of the cimetidine group. Among severe patients in China, it was generally well tolerated and no new safety issues were found.

Esomeprazole (Nexium, esomeprazole) is available in oral and injection forms. For gastric and duodenal ulcers: 20 mg each time, taken once in the morning. The treatment course for duodenal ulcer is usually 2 to 4 weeks, and the treatment course for gastric ulcer is 4 to 8 weeks.

Esomeprazole (Nexium, esomeprazole) can be used for patients with refractory ulcers, 20 mg twice a day or 40 mg once a day.

When taking esomeprazole (Nexium, esomeprazole), the tablet should be swallowed whole together with the liquid. It should not be chewed or crushed, otherwise it will affect the efficacy of the medicine. For patients who cannot swallow, esomeprazole (Nexium) can be dissolved in carbonate-free water and given through a gastric tube.

The above is the introduction about (Nexium, esomeprazole), I hope it can help everyone. If patients have other questions about the drug (such as drug price, purchasing channels, etc.), they can consult the medical companion travel service.

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