氯法齐明是抗生素吗,属于激素药吗?
Currently, drug-resistant tuberculosis, especially multidrug-resistant tuberculosis, has become one of the three major challenges in tuberculosis control. Multidrug-resistant tuberculosis (MDR-TB) means that Mycobacterium tuberculosis is resistant to at least isoniazid and rifampicin. my country is one of the countries with severe MDR-TB epidemics. Many studies have shown that insufficient or inappropriate tuberculosis medication is the main reason for the occurrence of MDR-TB.以往在临床上药物是治疗麻风病的主要药物之一,近年来研究发现氯法齐明对治疗耐多药肺结核具有显著疗效,那么,氯法齐明是抗生素吗,属于激素药吗?
Is clofazimine an antibiotic?
氯法齐明是一种比较高档的抗生素,耐多药结核患者使用氯法齐明进行治疗,可干扰其体内结核分枝杆菌细胞的能量代谢及核酸代谢的过程,进而可使其体内的结核分枝杆菌发生调亡。 The research results of Liu Baishan et al. show that compared with other anti-tuberculosis drugs, clofazimine has a stronger effect against Mycobacterium tuberculosis. Shi Haiping et al. used clofazimine combined with second-line anti-tuberculosis drugs to treat multidrug-resistant tuberculosis and achieved remarkable results.
Is clofazimine a hormonal drug?
Clofazimine is a specialized drug used to treat leprosy. It is produced in accordance with the National Pharmacopoeia and does not contain hormone ingredients.氯法齐明具有较强的脂质亲和力,口服后沉积于脂肪组织及网状内皮系统内,并被全身巨噬细胞吸收,可能产生皮肤红染,皮肤干燥以及恶心、呕吐、便秘以及腹痛等消化道不良反应;主要通过尿液、痰液以及乳汁排出体外,因此消化系统溃疡及肝肾功能不全者慎用,妊娠、哺乳期患者禁用。
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