2023阿普斯特片多少钱？

Apremilast is a small molecule PDE4 inhibitor developed by the American company Celgene. In current clinical research trials, it will be used in the treatment of plaque psoriasis and other related skin diseases. Research has confirmed that Apremilast can specifically select PDE4 as its target in the treatment of psoriasis, thereby regulating the expression levels of pro-inflammatory, anti-inflammatory and other mediator factors in human innate immune cells. It can effectively increase the cAMP level in human cells while activating the dependence of cAMP protease A. It can also activate cyclic nucleotide-gated ion channels, promote the activation of cAMP/protease A and trigger the cAMP response in transcription factors. The phosphorylation process of the binding family of components activates transcription factors. So, how much does Apremilast tablets cost in 2023?

How much does Apremilast tablets cost in 2023?

In August 2021, Amgen’s original Apremilast tablets were approved for marketing in China for the treatment of adult patients with moderate to severe plaque psoriasis who are eligible for phototherapy or systemic therapy. This is the first oral phosphodiesterase 4 (PDE4) inhibitor approved for the treatment of plaque psoriasis in China. According to information on Drugs.com, the typical dose of Apremilast is 30 mg taken by mouth twice daily in a bottle of 60 tablets. Depending on this dosage, each bottle is generally between US$2,000 and US$2,500, which means the price per tablet is between US$33 and US$42, which can be said to be relatively expensive.

Prices of other versions of 2023 Apremilast tablets

Because imported Apremilast tablets are expensive, many patients choose to use overseas versions of Apremilast for treatment. Glenmark India's Apremilast has a specification of 30mg*30 capsules and a price of about 160$, and a specification of 30mg*60 capsules and a price of about 230$, which is very suitable for long-term use by patients. At present, the most suitable overseas method for patients is to find domestic and overseas medical service institutions to help them purchase Apremilast tablets. First, when purchasing drugs, a three-party contract must be signed to ensure the quality and authenticity of the drugs. Secondly, the method of purchasing drugs is overseas direct mail. Patients only need to sit at home and wait for the drugs to be mailed directly to their door, which is very convenient and reliable.

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