银屑病用药阿普斯特(Apremilast)的副作用和处理措施？

The side effects of the psoriasis drug Apremilast mainly include diarrhea, nausea, upper respiratory tract infection, tension headache, headache, abdominal pain, vomiting, fatigue, indigestion, loss of appetite, insomnia, back pain, migraine, etc. Targeted treatment is required based on different side effects.

Apremilast side effects

The main ones include diarrhea, upper respiratory tract infection, tension headache, headache, abdominal pain, vomiting, fatigue, indigestion, loss of appetite, insomnia, back pain, migraine, increased bowel frequency, depression, bronchitis, tooth abscess, folliculitis, etc. For different symptoms, treatment measures will also be different.

Measures to deal with side effects of Apremilast

1. Diarrhea: Maintain adequate fluid intake, add more fluids to prevent dehydration, and follow the doctor's recommendations to use antidiarrheal drugs, such as montmorillonite powder, and avoid spicy, cold, and cold foods.

2. Upper respiratory tract infection: Pay attention to rest, keep warm, and drink more water. If accompanied by fever, headache, muscle aches and other symptoms, antipyretic and analgesic drugs, such as ibuprofen, can be used under the guidance of a doctor.

3. Tension headache: You can relax through appropriate outdoor activities, listening to music, etc. You can also try relaxation techniques such as head massage or deep breathing to relieve symptoms. If the headache is severe, you can use painkillers, such as acetaminophen, with your doctor's advice.

4. Headache: It can be relieved by resting, relaxing, and massaging the head.

5. Abdominal pain: Pay attention to dietary hygiene, avoid consuming irritating foods, and avoid eating greasy and irritating foods.

6. Vomiting: Avoid irritating food, such as greasy food and spicy food. If vomiting is severe, seek medical advice and use antiemetics as recommended by your doctor.

7. Fatigue: Pay attention to rest and sleep, avoid overexertion, ensure adequate sleep time, and avoid staying up late.

8. Indigestion: Pay attention to dietary hygiene and avoid eating greasy, spicy or difficult-to-digest foods. Do not lie down immediately after eating. You can promote food digestion and absorption by taking a walk after a meal and other methods.

9. Decreased appetite: You can try to eat smaller meals more frequently and choose foods that are easy to digest, low in fat, and low in fiber to increase appetite.

10. Insomnia: Create a good and comfortable sleeping environment and avoid drinking irritating drinks such as coffee, tea or cola before going to bed.

11. Back pain: You can relieve muscle pain through hot compress, massage, massage and other methods, and maintain correct sitting and standing postures.

12. Migraine: You can try relaxation techniques such as proper head massage or deep breathing to relieve symptoms.

13. Increased frequency of defecation: Pay attention to dietary hygiene and avoid consuming irritating foods. If defecation is excessive and lasts for a long time, it is recommended to seek medical treatment and receive appropriate treatment.

14. Depression: You can consult a psychologist or psychiatrist for professional advice and treatment plans.

15. Bronchitis: You need to rest and maintain a well-ventilated indoor environment, and follow your doctor’s recommendations for antibiotics or other treatments.

16. Tooth abscess: Treatment may require antibiotics or abscess drainage.

17. Folliculitis: Pay attention to skin cleanliness and hygiene. Use non-irritating antibacterial products or warm water to wash the affected skin.

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1. Follow the doctor's instructions: Please use Apremilast according to the doctor's instructions and prescriptions, and strictly follow the dosage and frequency of medication. Do not change your dose or stop using Apremilast unless directed by your doctor.

2. Liver function monitoring: Liver function tests may be required before starting to use Apremilast, and liver function should be monitored regularly during treatment. If you develop symptoms of abnormal liver function, such as fatigue, jaundice, or nausea, please inform your doctor immediately.

3. Pregnant and lactating women: Apremilast may have adverse effects on the fetus or infant. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will weigh the benefits and risks and decide whether to continue using Apremilast or find an alternative treatment.

4、感染风险：阿普斯特可能降低免疫系统的功能，增加感染的风险。 Avoid close contact with infected people and follow good hygiene while using Apremilast. If you develop any symptoms of infection, such as fever, cough, sore throat, etc., please inform your doctor immediately.

5. Drug interactions: When using Apremilast, it may interact with other drugs. Before using Apremilast, inform your doctor of other medications you are using, including prescription drugs, over-the-counter drugs, and supplements, to avoid potential interactions.

Summary

The psoriasis drug Apremilast has many side effects, and the treatment measures will be different for different symptoms. If the symptoms are severe or last for a long time, it is recommended to seek medical treatment promptly and receive professional treatment. At the same time, maintaining good living habits and a healthy lifestyle is also one of the important factors in preventing and treating these symptoms.

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