阿普斯特多少钱一盒?在哪里购买?

Apremilast is a drug that treats psoriasis, active psoriatic arthritis and other diseases. Its price varies depending on factors such as version, region and sales channel. This article will detail the price range, purchase channels, and pharmacokinetic properties of Apremilast to help patients better understand and use this drug.

How much does a box of Apremilast cost?

The price varies depending on factors such as version, region and sales channel, and the price is for reference only.

In the Chinese market, Apremilast has been launched in China and has been included in medical insurance. The winning price of medical insurance ranges from approximately US$51 to US$70. The price after reimbursement will be lower and needs to be calculated according to the specific reimbursement ratio.

Apremilast produced by Glenmark in India has two specifications, with different specifications and different prices. The price of a box of 30mg*30 pills is about US$22, and the price of a box of 30mg*60 pills is about US$32.

Where to buy Apremilast

Apremilast is a prescription drug that requires a doctor's prescription when purchased. Patients can obtain it through the following formal channels:

Hospital pharmacy

Hospital pharmacy is a common way for patients to obtain Apremilast. After the patient visits the hospital, the doctor will issue a prescription according to the condition, and the patient can purchase the drug at the hospital pharmacy with the prescription. Hospital pharmacies usually have a team of professional pharmacists who can provide patients with medication guidance and consultation services to ensure patients use medications safely and rationally.

Online pharmacies

With the popularity of the Internet, online pharmacies have also become a convenient choice for patients to purchase Apremilast. When choosing an online pharmacy, patients should ensure that the pharmacy has legal sales qualifications and a professional pharmacist team that can provide doctors with online prescription services. At the same time, patients should also pay attention to protecting personal information and payment security to avoid losses due to online fraud.

Regular medical service institutions

For some versions that are not yet on the market in China or have higher prices, patients can also purchase them through formal medical service institutions. After placing an order, they can obtain the drugs through direct mail, which is more convenient and fast.

Pharmacokinetics of Apremilast

Apremilast is an oral, small molecule phosphodiesterase 4 (PDE4) inhibitor with good bioavailability and pharmacokinetic properties. Understanding the pharmacokinetic properties of Apremilast can help patients better understand medication timing and dose adjustment.

Absorption and Distribution

After oral administration, Apremilast can be rapidly absorbed from the gastrointestinal tract and enters the blood circulation. Its peak plasma concentration time (Tmax) is about 2.5 hours, and its bioavailability is high. In the human body, Apremilast has a high binding rate to plasma proteins, about 68%, which contributes to the stable existence and distribution of the drug in the body.

Metabolism and Excretion

Apremilast is mainly metabolized in the human body through the cytochrome P450 (CYP) enzyme system to generate a variety of metabolites. Among them, some metabolites still have pharmacological activity and can continue to exert therapeutic effects. Apremilast and its metabolites are mainly excreted through urine and feces, with a half-life of approximately 6-9 hours. This means that when patients take Apremilast, they need to take it according to the prescribed dosage interval to maintain stable blood concentration and therapeutic effect.

The price of Apremilast varies depending on factors such as version, region and sales channel. Patients should choose the appropriate version and channel based on their own financial situation and doctor's advice when purchasing.