阿普斯特有哪几个版本?分别多少钱?

Apremilast is an oral drug used to treat psoriasis and psoriatic arthritis. Versions produced by different pharmaceutical companies vary in price and strength. This article will provide patients with comprehensive medication reference information from three aspects: drug version classification, market price comparison, and clinical treatment effect.

What versions of Apremilast are there

There are multiple versions around the world, mainly including original drugs and generic drugs. The different versions are basically the same in terms of ingredients and efficacy.

Original drug version

The original drug Otezla was developed by the American company Celgene and has been approved by the FDA and EMA. This version has undergone complete clinical trials, has the most comprehensive data, and is sold in many countries around the world.

Generic versions

The generic versions produced by Indian pharmaceutical companies such as Glenmark and Cipla have been approved by the corresponding national drug regulatory authorities. These versions are consistent with the original drugs in terms of active ingredients, and the production process complies with international standards.

Common specifications

The common specifications of Apremilast on the market include 30mg×30 capsules and 30mg×60 capsules. Some manufacturers also provide 10 mg and 20 mg strengths for dosage adjustment.

When choosing a version, patients should give priority to drug quality and supply stability, and choose a suitable treatment plan under the guidance of a doctor.

How much do different versions of Apremire cost?

The price of Apremilast varies greatly depending on the version, specifications and purchase channels. The following is the market reference price of the main versions.

Original drug price

Otezla, the original drug, is priced relatively high in the U.S. market, with a price of about US$4,700 for 30 mg × 60 capsules. In some European countries, the proportion of patients paying out-of-pocket has been significantly reduced after reimbursement through medical insurance.

Prices of generic drugs in India

Apremilast produced by Glenmark Pharmaceuticals in India is available in two specifications. The price of 30mg×30 tablets is about US$22 per box, and the price of 30mg×60 tablets is about US$32 per box.

Prices of other generic versions

The price of generic versions of Cipla and other Indian pharmaceutical companies is similar to Glenmark, with the price range of 30mg×30 capsules ranging from US$20 to US$25. The price of the Bangladeshi version is slightly higher, about US$30-35/box.

Patients can obtain the latest price information through formal cross-border medical platforms, and pay attention to comparing quotations and service quality from different channels.

The efficacy of Apremilast

Apremilast exerts a therapeutic effect by specifically inhibiting PDE4, and has shown significant effects in the treatment of psoriasis and related arthritis.

Psoriasis treatment effect

Clinical studies have shown that some patients reached the PASI75 standard (the area and severity of skin lesions improved by more than half) after 16 weeks of medication, and their itching symptoms were significantly relieved.

Improvement of arthritis symptoms

For patients with psoriatic arthritis, Apremilast can effectively reduce joint swelling and pain, improve joint function, and some patients have reached the ACR20 relief standard.

Safety performance

Compared with biological agents, the adverse reactions of Apremilast are relatively mild, with common gastrointestinal symptoms such as diarrhea and nausea, which usually gradually reduce as the medication time is extended.

Apremilast provides a convenient oral treatment option for patients with moderate to severe psoriasis, and its efficacy has been verified by multiple clinical trials.