罗氟司特乳膏的用药指南

Roflumilast cream (is a new topical phosphodiesterase 4 (PDE4) inhibitor, mainly used for plaque psoriasis and atopic dermatitis. Correct usage is crucial to reduce adverse reactions. This article will explain in detail the usage and dosage of roflumilast cream, common side effects and medication for special groups to help patients and medical staff use the drug rationally.

Roflumilast cream Usage and Dosage

Usage must strictly follow medical instructions. The correct medication method directly affects the therapeutic effect and safety.

Standard Usage

Roflumilast cream should be applied evenly once a day. Apply to the affected area and rub gently until fully absorbed. Clean and dry the skin before use, and avoid using it with other topical drugs. Each dosage should cover the entire affected area, but should not exceed 20% of the body surface area.

Duration of use.

Patients with plaque psoriasis usually need to use it for 8 weeks. Patients with atopic dermatitis can observe symptom improvement within 4 weeks. If symptoms persist or worsen, you should consult your doctor to adjust the treatment plan.

Precautions after use

Wash your hands thoroughly after application, unless used to treat hand lesions. Avoid contact with the eyes, mouth, and genital mucosa. The application site should not be bandaged or covered to avoid accidental contact with the eyes. , rinse immediately with water for 15 minutes.

Following correct usage can maximize the therapeutic effect of roflumilast cream while reducing the risk of adverse reactions.

Side effects of roflumilast cream

Roflumilast cream may cause local and systemic adverse reactions. Understanding these reactions can help with timely identification and management.

Local skin reactions

Common application site reactions include stinging, burning, and pruritus. Itching and erythema, these symptoms are usually mild and short-lived, and usually appear in the initial stage of medication, and gradually reduce as the skin adapts.

Systemic adverse reactions

Diarrhoea, headache and insomnia are the most common systemic reactions. A small number of patients may experience upper respiratory tract infection and urinary tract infection. These reactions are mostly mild to moderate and rarely lead to treatment interruption.

Severe adverse reactions

A very small number of patients may experience allergic reactions, such as rash, Difficulty breathing or facial swelling. If severe skin irritation or systemic symptoms occur, stop taking the drug and seek medical attention immediately. Long-term use requires monitoring of weight changes, as some patients may experience unexplained weight loss.

Being aware of these side effects can help patients stay vigilant during use and seek medical help in time when necessary.

Special groups should use roflumilast cream with special caution, and medication may need to be adjusted. Program.

Pediatric patients

Children aged 2 years and above can be used for the treatment of atopic dermatitis, with a concentration of 0.05% recommended. Children aged 6 years and above can be used for the treatment of plaque psoriasis, with a concentration of 0.3%. . The area of application should be more strictly controlled and large-area use should be avoided.

Pregnant women and lactating women

Using by pregnant women should only be considered when the potential benefits outweigh the risks. In the nipple and areola area, avoid direct contact of infants with the medication site.

Elderly patients and patients with liver and kidney dysfunction

Dosage adjustment is not required for patients with moderate to severe liver dysfunction. Patients with renal impairment do not need to adjust the dose, but adverse reactions still need to be closely monitored.

Special groups need individualized assessment, and doctors should develop appropriate treatment plans based on the patient's specific conditions.