服用奥拉迪约需要注意哪些方面?奥拉迪约有什么副作用?
Orladeyo is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in adults and children over 12 years of age. Orladeyo is not used to treat acute HAE attacks. Do not take more than one capsule per day as overdose may cause heart rhythm problems. It is not known whether Orladeyo is safe and effective in treating acute HAE attacks. It is not known whether this drug is safe and effective in children under 12 years old.
Precautions when taking Oradejo:
Risk of QT prolongation at higher than recommended doses: Orladeyo should not be used to treat acute exacerbations of HAE. Additional once daily doses or doses higher than 150 mg of Orladeyo are not recommended. A concentration-dependent increase in QT was observed at doses above the recommended daily dose of 150 mg.
Drug Interactions: Inform patients that Orladeyo may interact with other drugs. Advise patients to report the use of any other prescription or over-the-counter medications or herbal products to their physician.
Not indicated for the acute treatment of acute ischemic encephalopathy attacks: Advise patients to take commonly used rescue medications for the treatment of acute ischemic encephalopathy attacks. Inform patients that the safety and effectiveness of using Orladeyo as an acute treatment for HAE attacks has not been established. Advise patients not to take daily doses of more than 150 mg or additional doses of Orladeyo once daily to treat acute attacks of HAE due to the risk of QT prolongation
What are the side effects of Oradejo?
Heart rhythm problems. Taking more than one Orladeyo capsule a day may cause heart rhythm problems with QT prolongation, a condition that causes an abnormal heartbeat. The most common adverse reactions (≥10%) were abdominal pain, vomiting, diarrhea, back pain, and gastroesophageal reflux disease. Less common side effects include: Abnormal liver function tests. Less common side effects: Brief, itchy rash.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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