一直以来,你真的用对贝罗司他胶囊了吗?
Hereditary angioedema (HAE) is a rare autosomal dominant disease clinically characterized by recurrent localized, self-limited subcutaneous or submucosal edema, often involving the skin, upper respiratory tract, and gastrointestinal tract. C1INH gene mutations lead to reduced serum C1INH protein concentration and/or functional defects, which are the main pathogenesis of the disease. HAE can be divided into three types according to serum C1INH concentration and functional level. The two most common types are type I and type II. It is an oral capsule approved for the prevention of hereditary angioedema (HAE) attacks in patients 12 years of age and older. Most HAEs are caused by a deficiency (type 1 HAE) or dysfunction (type 2 HAE) of a protein called C1 esterase inhibitor. Berosostat capsule is a plasma kallikrein inhibitor that binds to plasma kallikrein and inhibits its proteolytic activity. So, have you really been using Berostat capsules all this time?
It is very simple and only needs to be used once a day, preferably with food. The dosage is one capsule (150 mg) taken orally until the disease progresses. The side effects of Berostat capsules include abnormal liver function indicators, back pain, gastroesophageal reflux disease, abdominal pain, vomiting, transient itchy rash, heart rhythm problems, diarrhea, etc. Here is one thing the editor would like to remind everyone. If you are currently using berosstat capsules, the patient must strictly follow the doctor's instructions. Irregular medication may lead to aggravation of the disease and side effects. Only timely and quantitative medication according to the doctor's instructions can maximize the effect of the drug itself.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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