贝罗司他胶囊治疗效果如何？用多长时间能见到效果

Berosostat is a once-daily oral medication indicated for the prevention of hereditary angioedema (HAE) attacks in children and adults aged ≥12 years. It is worth mentioning that berotralstat capsules are the first targeted oral therapy approved to prevent HAE attacks. The approval of this drug will bring significant progress in the treatment of patients with hereditary angioedema (HAE) and help patients reduce their treatment burden. How effective is the treatment? How long does it take to see results?

In the pivotal Phase 3 APeX-2 trial, berotralstat significantly reduced the number of HAE episodes over 24 weeks and continued through week 48. Patients who completed the 48-week trial experienced a significant reduction in the frequency of hereditary angioedema (HAE) attacks, from an average of 2.9/month at baseline to an average of 1/month. In another long-term open-label APeX-S study, patients' frequency of hereditary angioedema (HAE) attacks was reduced to an average of 0.8 attacks per month.

The results of the above two clinical trials show that berotralstat capsules are safe and well tolerated, can significantly reduce the frequency of hereditary angioedema (HAE) attacks, improve patients' quality of life, and have a positive effect on the patient's condition. The launch of this drug has brought new treatment options to many patients with hereditary angioedema (HAE).

Because each patient's condition, personal constitution, and tolerance to drugs are different, the effective time and therapeutic effect after treatment with berotralstat capsules will also be different. The effective time after treatment with berotralstat capsules is mainly determined by the patient's disease stage, personal constitution, and drug tolerance. There is no accurate time point. When patients receive berotralstat capsules (berotralstat), they follow the correct usage method and I believe they will have good results soon.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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