贝罗司他胶囊长期用会耐药吗？会出现哪些不良反应

Berostat (Orladeyo) is a plasma kallikrein inhibitor indicated for the prevention of hereditary angioedema (HAE) in adults and pediatric patients over 12 years of age. But patients should note: This medicine should not be used to treat acute hereditary angioedema (HAE) attacks. Berostat capsules (Orladeyo) are the first targeted oral therapy approved to prevent HAE attacks. The approval of the drug will bring significant progress in the treatment of patients with hereditary angioedema (HAE) and help reduce the treatment burden on patients. Will it be resistant to long-term use? What adverse reactions may occur?

Berostat capsule drug resistance

Long-term use of drug treatment will lead to drug resistance, and long-term treatment with beroxostat capsules (Orladeyo) will also lead to drug resistance. Each patient has different tolerance levels to drugs, as well as disease progression and physical conditions. This is because the time it takes for patients to develop resistance after treatment with Orladeyo, the specific manifestations of drug resistance, and the treatment methods after drug resistance are also different. The specific time, performance, and treatment methods of drug resistance are determined by the patient's own situation.

Patients who develop resistance to beroxostat capsules (Orladeyo) should not use other drugs without authorization, because incorrect medication may lead to other adverse reactions. Therefore, patients should go to the hospital promptly after developing drug resistance, where professional doctors will provide diagnosis and treatment and adjust the medication plan.

Adverse reactions of berosostat capsules include: back pain, gastroesophageal reflux disease, abnormal liver function indicators, heart rhythm problems, abdominal pain, vomiting, diarrhea, transient/itchy rash, etc. Not all of the above adverse reactions will occur. Depending on the patient's disease progression, personal constitution and tolerance to the drug, the side effects produced by the patient will also be different. If patients experience serious side effects during treatment with Berostat Capsules (Orladeyo), they should go to the hospital in time and a professional doctor will adjust the medication plan.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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