他克莫司软膏主要治疗哪些病症？作用功效是什么

Tacrolimus ointment is an immunomodulator with a macrolide structure and has obvious anti-inflammatory effects. Tacrolimus ointment has a special macromolecular structure and can release antihistamines, which can effectively prevent the aggravation of dermatitis. Tacrolimus ointment can also prevent the excessive proliferation of inflammatory cells. This drug can be absorbed by cells after entering the human body, so its effect is relatively strong. What diseases are mainly treated? What is the function?

Tacrolimus ointment indications

Tacrolimus ointment (tacrolimus) is mainly used as a short-term or intermittent long-term treatment in patients with moderate to severe atopic dermatitis who are not suitable for traditional treatments due to potential risks, or who have an inadequate response to traditional treatments, or who are unable to tolerate traditional treatments. Both 0.03% and 0.1% concentrations of tacrolimus ointment (tacrolimus) can be used in adults, but only 0.03% concentration of tacrolimus ointment can be used in children 2 years and older.

Tacrolimus ointment effects

In patients with atopic dermatitis, improvement in skin lesions during tacrolimus ointment treatment was associated with a reduction in Fc receptor expression on Langerhans cells and a reduction in their hyperstimulatory activity on T cells. Tacrolimus ointment does not affect the body's collagen synthesis.

A total of 171 clinical adult patients with atopic dermatitis were randomly divided into 3 groups in a ratio of 1:1:1, and were treated with 0.1% and 0.03% tacrolimus ointment and 0.05% desonide cream (control group) respectively. The test results showed that the overall treatment rate, clinical evaluation and patient evaluation of 0.1% tacrolimus ointment were higher than those of the control group. Tacrolimus ointment has a significant therapeutic effect, can improve the patient's quality of life, and has a positive effect on the patient's condition.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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