他克莫司软膏能治疗唇炎吗？

Tacrolimus is a powerful macrolide immunosuppressant isolated from the broth culture medium of the soil fungus Streptomyces. Its molecular weight is smaller than cyclosporine A (CsA), but its immunosuppressive effect is 10 to 100 times stronger than CsA. In addition, tacrolimus can also inhibit the release of histamine, leukotrienes and prostaglandins from basophils and mast cells, and has a strong anti-inflammatory effect. In 1989, Starzel et al. first applied tacrolimus to organ transplantation, and later found that it was effective in a variety of immune-related diseases. Since 2001 and pimecrolimus ointment has been approved for the treatment of atopic dermatitis.

Can tacrolimus ointment treat cheilitis?

Tacrolimus ointment (tacrolimus) is generally used to treat some refractory dermatitis, but the effect may not be ideal for patients with cheilitis. In addition, tacrolimus ointment cannot be taken orally to avoid causing serious adverse reactions. Therefore, when you have cheilitis, try not to apply tacrolimus ointment to avoid accidentally taking it. Patients with cheilitis can take appropriate vitamin supplements and apply VE ointment externally.

The future of tacrolimus ointment is promising

As the first successfully developed external immunomodulator, tacrolimus ointment is convenient, effective and safe for topical application. With in-depth research on the mechanism of action of tacrolimus and its application in other skin diseases other than atopic dermatitis, its indications may gradually expand. With the development of various physical therapies, TAC administration methods can take various forms, including microneedles and packets. Maintenance treatment with topical tacrolimus ointment can prevent recurrence and reduce the economic burden caused by drugs.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.