鲁索替尼乳膏应该如何使用？不良反应多不多

Atopic dermatitis is a chronic immune-mediated disease in which inflammation and itching are the most characteristic symptoms. Signs and symptoms include itchy skin that may result in deep and crusted red lesions. Ruxolitinib cream is a Janus kinase (JAK) inhibitor that selectively inhibits JAK1/JAK2. The FDA has approved ruxolitinib cream (Opzelura) for the short-term or non-sustained chronic treatment of patients with mild to moderate atopic dermatitis (AD). This is the first and only topical preparation of a JAK inhibitor approved by the US FDA. How should it be used? Are there many adverse reactions?

How to use ruxolitinib cream

The recommended dose of ruxolitinib cream (Opzelura) is to apply a thin layer of the product to no more than 20% of the affected area of the body twice daily. The weekly dosage should not exceed 60g. Ruxolitinib cream (Opzelura) is for topical use only and not for ophthalmic, oral, or intravaginal use.

Discontinue use of ruxolitinib cream (Opzelura) when the signs and symptoms of atopic dermatitis subside. If the patient's signs and symptoms do not improve within 8 weeks of treatment with the drug, the patient's physical condition will need to be re-examined by a healthcare provider. When patients receive ruxolitinib cream (Opzelura) and follow the correct usage method, they believe they will have good results soon.

Ruxolitinib cream adverse reactions

Common adverse reactions to ruxolitinib cream (Opzelura) include: pain or swelling in the nose or throat, diarrhea, bronchitis, ear infection, increased eosinophil count, hives, folliculitis, tonsillitis, runny nose, etc. Because each patient's condition and tolerance to drugs are different, the side effects and side effects experienced by patients after receiving ruxolitinib cream (Opzelura) treatment will also be different and cannot be generalized. If patients have serious side effects during treatment, they should not use other drugs without authorization. They should go to the hospital in time and seek help from professional doctors to avoid delaying the condition.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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