鲁索替尼乳膏(Ruxolitinib cream)最新公布价格表

With the rapid development of medical technology, more and more innovative drugs have been developed and put into the market, bringing new treatment hope to many patients. Ruxolitinib cream Cream), as a high-profile topical drug, its price and efficacy have always been the focus of attention of patients and the medical community. This article will introduce the latest price information of original drugs and generic drugs, and deeply explore the mechanism of action of ruxolitinib cream.

The latest price list of Ruxolitinib cream

The market price of the original product (60g specification) produced by Incyte in the United States is about $10,800 per box.

The price of generic ruxolitinib cream (30g specification) produced by Bangladesh Yaopin International is more affordable, about $400 per box.

Mechanism of action of Ruxolitinib cream

JAK signaling pathway inhibition: Ruxolitinib cream is a Janus kinase (JAK) inhibitor that mainly inhibits the activities of JAK1 and JAK2. JAK is a class of enzymes that mediate cell signaling and plays a key role in cytokine and growth factor signaling. By inhibiting the JAK signaling pathway, ruxolitinib can block signal transduction downstream of cytokine receptors, thereby reducing inflammatory responses and immune cell activation.

Regulate gene expression: JAK signaling involves the recruitment, activation and nuclear localization of STATs (signal transducers and activators of transcription). This process plays an important role in regulating gene expression. By inhibiting this signaling pathway, ruxolitinib can affect the expression of genes related to skin diseases, thereby improving the symptoms of skin diseases.

Clinical application: In clinical trials, ruxolitinib cream has demonstrated significant efficacy in a variety of skin diseases, including chronic plaque psoriasis, vitiligo, and atopic dermatitis. It not only reduces symptoms such as skin scales, erythema, itching and inflammation, but also promotes skin repair and pigment restoration. Especially for patients with atopic dermatitis, ruxolitinib cream can quickly relieve itching and inflammation and significantly improve the patient's quality of life.

Ruxolitinib cream, as an innovative topical drug, has shown broad application prospects in the field of dermatology treatment. Whether it is original drugs or generic drugs, they provide patients with effective treatment options. However, patients still need to be cautious when selecting and using them, and follow their doctor's recommendations.