绥美凯是什么时候上市的呢？

It is a once-daily three-in-one drug developed by ViiV Healthcare, a joint venture between GlaxoSmithKline and Pfizer. The drug is based on the treatment plan of the integrase inhibitor Tivicay (Dolutegravir) and also contains two nucleoside reverse transcriptase inhibitors, Abacavir and Lamivudine. It was approved by the FDA on August 27, 2014.

Subsequently, on January 22, 2018, GlaxoSmithKline (GSK) announced that its single-tablet compound preparation dolutegravir (Triumeq), which is based on the new generation integrase inhibitor dolutegravir (DTG) and is used to treat HIV, was officially launched in mainland China. This is the first single-pill compound preparation with a complete treatment plan in the field of HIV treatment in mainland China.

The Dolutegra abalami tablets (Suimeike, Inbec) launched this time are China’s first complete single-tablet three-in-one preparation with DTG as the core, filling the gap in single-piece compound preparations. GSK has previously had a DTG drug on the market, with the trade name Tevicay. It was launched in the United States in 2013, but it needs to be used in combination with other drugs. Dolutegra abalami tablets are a complete single-tablet three-in-one preparation with DTG as the core. It can be taken once a day, one tablet at a time, without considering factors such as food, environment, location, etc. AIDS is generally recognized as a chronic disease, and for chronic diseases, patient compliance is particularly important. Doptabalamid tablets, one tablet once a day, reduce the frequency and dosage of medication, and significantly enhance patient compliance.

Adverse reactions of / dote abalamide tablets include gastrointestinal - nausea, vomiting, diarrhea, abdominal pain, mouth ulcer; neurology/psychiatry - headache, paresthesia; hematology - lymphopenia; liver/pancreas - increased liver function indicators; muscle and bone - myalgia, myolysis, arthralgia, increased creatine phosphatase; respiratory - dyspnea, sore throat, cough, influenza-like syndrome; skin - rash (usually maculopapular rash and urticaria) ; Urology - elevated creatinine, renal failure; Other - fever, lethargy, malaise, edema, lymphadenopathy, hypotension, conjunctivitis, allergies.