双氢睾酮外用凝胶:在治疗男性乳房发育症中的作用

Introduction: Dihydrotestosterone (DHT) is a hormone that plays a key role in the sexual development of people assigned male at birth (AMAB). More specifically, DHT is a hormone that stimulates the development of male characteristics. The mechanism of action of dihydrotestosterone topical gel in the treatment of gynecomastia is mainly achieved by regulating hormone balance in the body.

Gynecomastia

Gynecomastia is usually caused by relatively high estrogen levels or relatively insufficient testosterone levels, leading to the proliferation of breast tissue. Dihydrotestosterone, the more potent metabolite of testosterone, can increase androgenic activity locally or systemically, thereby helping to restore or maintain normal androgen to estrogen ratios.

The effect of dihydrotestosterone topical gel

It has an estrogen-inhibiting effect, and the increased DHT level helps to counteract the estrogen effect, because DHT can competitively bind to estrogen receptors in some tissues and reduce estrogen-driven breast tissue growth. Dihydrotestosterone topical gel also has an androgenic effect. DHT directly acts on the breast and other tissues to promote the maintenance and development of male characteristics and help reverse breast hyperplasia caused by androgen deficiency. In addition, dihydrotestosterone topical gel may help adjust the hormonal environment in the body by exogenously supplementing DHT, especially when the conversion of naturally produced testosterone to DHT in men is affected.

Usage Guidelines

It is recommended that patients strictly follow the drug instructions or doctor's instructions for use, including medication site, dosage and frequency. It is usually necessary to apply evenly on clean, dry skin and avoid applying to damaged skin. Wash hands after use.

Notes

It should be noted that although dihydrotestosterone gel can help treat gynecomastia, its actual application and treatment effects vary from person to person. Patients should consult a doctor before taking medication and proceed under the guidance of a doctor. They must not take medication privately. In addition, some side effects may occur with the use of dihydrotestosterone gel, such as skin irritation, acne, increased hair growth, prostate problems, mood changes, etc. Therefore, it is necessary to regularly check serum prostate-specific antigen (PSA) levels, prostate volume, and liver function during treatment to monitor adverse drug reactions.