双氢睾酮外用凝胶导致的不良反应怎么治疗？

Introduction: Testosterone can be directly or first converted into the more active dihydrotestosterone, which binds to androgen receptors in spermatogenic cells to promote sperm production. Therefore, the main function of dihydrotestosterone topical gel is to maintain sperm production, stimulate the development of reproductive organs, promote the appearance of male secondary sexual characteristics and maintain their normal shape, and maintain normal sexual desire.

Adverse reactions caused by dihydrotestosterone topical gel

1. Impact on bone development: If used by pre-pubescent people, it may accelerate bone development and prematurely close the epiphysis, thus affecting height.

2. It may aggravate prostatic hypertrophy: Dihydrotestosterone is an androgen, and the prostate is an androgen-dependent organ. Excessive androgens will aggravate prostatic hypertrophy.

3. Skin irritation: As a topical gel, dihydrotestosterone topical gel may cause certain irritation to the skin, especially for users with sensitive skin.

4. Endocrine effects: Long-term or improper use may cause endocrine imbalance and affect the body's natural hormone levels.

5. Mood and behavioral changes: Dihydrotestosterone topical gel may affect mood and behavior, especially at higher doses or with long-term use.

6. Body hair growth: Dihydrotestosterone topical gel may promote the growth of body hair, especially in female patients.

7. Hair loss: Long-term high levels of dihydrotestosterone may cause hair loss.

When using dihydrotestosterone topical gel, you should strictly follow the doctor's instructions and conduct regular medical monitoring to reduce the risk. If any discomfort occurs during use, discontinue medication immediately and consult a doctor.

Treatment methods for adverse reactions of dihydrotestosterone topical gel

1. Skin irritation: If skin irritation occurs, you can consider reducing the dosage or frequency of use, or changing the application site. If irritation persists or worsens, a doctor should be consulted.

2. Extra hair growth: Usually it will gradually recover after stopping the drug. If the situation is serious, you can ask your doctor whether other treatment measures are needed.

3. Skin irritation: Oily skin can be managed by using mild skin cleansers and moisturizing products. If acne occurs, ask your doctor to recommend appropriate skin care products or treatments.

4. Influence on bone development: Children before puberty should use it under the guidance of a doctor to avoid accelerating bone development.

Special population use of dihydrotestosterone topical gel

1. Pregnant women: Dihydrotestosterone topical gel is contraindicated during pregnancy or in women who may become pregnant. Testosterone is teratogenic and may cause harm to the fetus. Exposure of female fetuses to androgens may result in varying degrees of virilization. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be informed of the potential harm to the fetus.

2. Breastfeeding women: Although it is unclear how much testosterone is transferred into breast milk, dihydrotestosterone topical gel is contraindicated in nursing women because it may cause serious adverse reactions in a nursing infant.

3. Children: The safety and effectiveness of dihydrotestosterone topical gel for men under 18 years of age have not been confirmed. Improper use may lead to accelerated bone age and premature closure of the epiphysis.