希爱力(Tadalafil)的副作用和不良反应

Some side effects of Cialis (Tadalafil) may not require medical intervention and may disappear during treatment as the body adjusts to the drug. It is recommended to inform your doctor promptly if side effects occur.

Side effects of Cialis (Tadalafil) that require immediate consultation with a doctor

1. Common side effects

Hiccups, heartburn (heartburn), indigestion, stomach discomfort, upset or pain.

2. Uncommon side effects

Nosebleeds, body aches or pains, burning sensation, ant crawling sensation, itching, numbness, stinging or pins and needles sensation, eye burning, dryness or itching, chest or stomach burning Sensation, nasal congestion, difficulty moving, difficulty swallowing, dry mouth, dry or painful throat, excessive eye secretions, eye pain, conscious or feeling that the surrounding environment is constantly moving (sense of motion), heat and redness in the face, neck, arms and occasionally upper chest.

Fever, hoarseness, fatigue or loss of energy, loose stools, muscle aches, cramps, or stiffness, neck pain, arm or leg pain, throat pain or burning, redness, pain, swelling, or decreased touch sensitivity of the eyes, eyelids, or lining of the eyelids, Runny or stuffy nose, dizziness (spinning feeling), drowsiness or unusual sleepiness, upset stomach, swollen eyelids, swollen or puffy eyes or face, swollen joints, watery eyes, tender and swollen glands in the neck, tenderness in the stomach area, sleep disturbance, upper abdominal pain, change in voice, watery eyes.

3. Rare side effects

Change in color vision.

The pictures come from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Side effects of Cialis (Tadalafil) that require immediate medical attention

1. Uncommon side effects

Arm, back or jaw pain, blurred vision, chest pain, discomfort, tightness or heaviness, chills, cold sweats, confusion, dizziness, fainting , feeling dizzy or lightheaded when suddenly rising from a lying or sitting position, fast or irregular heartbeat, headache, hearing loss, increased erection, nausea, nervousness, pain or discomfort in the arms, jaw, back or neck, pulsating sensation in the ears, heartbeat too slow or too fast, spontaneous penile erection, sweating, unusual tiredness or weakness, vomiting.

2. Rare side effects

Penile pain or persistent erection.

Side effects management for medical staff

1. Overall adverse events

The most commonly reported adverse reactions are headache, nausea, indigestion, back pain, myalgia, flushing, nasopharyngitis and limb pain. These adverse reactions are dose-dependent, transient, and usually mild or moderate.

2. Cardiovascular system

(1), very common (≥10%): flushing (up to 14%).

(2) Common (1%-10%): high blood pressure, hot flashes.

(3) Uncommon (0.1%-1%): hypotension.

(4). Frequency not reported: unstable angina, orthostatic hypotension, ventricular arrhythmia.

(5) Post-marketing reports: myocardial infarction, sudden cardiac death, stroke, chest pain, palpitations and tachycardia. These events are temporally related to taking this drug.

Most patients who experience side effects such as myocardial infarction, sudden cardiac death, stroke, palpitations, and tachycardia have existing cardiovascular risk factors. Many of the incidents reported occurred during or immediately after sexual activity.

3. Gastrointestinal tract

(1), very common (≥10%): indigestion (up to 13%), nausea (up to 11%).

(2) Common (1%-10%): diarrhea, gastroesophageal reflux disease, abdominal pain, gastroenteritis, constipation.

(3) Uncommon (0.1%-1%): Vomiting.

(4) Frequency not reported: dry mouth, dysphagia, esophagitis, gastritis, loose stools, nausea, upper abdominal pain, hemorrhoidal bleeding, and rectal bleeding.

4. Musculoskeletal system

(1), very common (≥10%): myalgia (up to 14%), back pain (up to 12%), limb pain (up to 11%).

(2). Common (1%-10%): limb pain and muscle stiffness.

(3) Uncommon (0.1%-1%): joint pain, muscle spasm.

(4). Frequency not reported: neck pain.

5. Nervous system

(1), very common (≥10%): headache (up to 42%).

(2). Common (1%-10%): dizziness (1%).

(3), rare (<0.1%): transient global amnesia, transient ischemic attack.

(4). Frequency not reported: hypoesthesia, drowsiness, syncope, and paresthesia.

(5). Post-marketing reports: migraine, epileptic seizures and epilepsy recurrence.

6. Respiratory system

(1), very common (≥10%): nasopharyngitis (up to 13%), upper and lower respiratory tract infections (up to 13%).

(2) Common (1%-10%): nasal congestion (including sinus congestion), cough, influenza, pulmonary hypertension, and rhinitis.

(3) Uncommon (0.1%-1%): dyspnea, nose bleeding.

(4). Frequency not reported: Pharyngitis.

7. Genitourinary system

(1) Common (1%-10%): urinary tract infection, menorrhagia (including uterine bleeding).

(2) Uncommon (0.1%-1%): Penile bleeding, bloody semen.

(3), rare (<0.1%): prolonged erection time.

(4). Frequency not reported: increased erection, spontaneous penile erection.

(5). Post-marketing report: Priapism.

8. Others

(1) Common (1%-10%): peripheral edema, fatigue, edema.

(2) Uncommon (0.1%-1%): tinnitus.

(3), rare (<0.1%): facial edema.

(4). Frequency not reported: dizziness, fatigue, pain.

(5) Post-marketing reports: There are reports of sudden hearing loss or hearing loss within a short period of time after using this drug.

In some cases, reported medical conditions and other factors may also play a role in the otologic adverse events. Medical follow-up information was limited in many cases.

9. Cutaneous system

(1), uncommon (0.1%-1%): rash, urticaria, hyperhidrosis (sweating).

(2), rare (<0.1%): angioedema.

(3). Frequency not reported: itching.

(4). Post-marketing reports: Stevens-Johnson syndrome, exfoliative dermatitis.

10. Eyes

(1) Uncommon (0.1%-1%): eye congestion, eye pain, eyelid edema.

(2), rare (<0.1%): color vision changes.

(3). Frequency not reported: blurred vision, conjunctivitis (including conjunctival congestion), eye pain, increased tear production.

(4). Post-marketing reports: visual field defects, retinal vein occlusion and retinal artery occlusion. Nonarteritic anterior ischemic optic neuropathy (NAION), a disorder that can cause decreased vision, including permanent vision loss, has been reported to be temporally associated with the use of this drug.

11. Kidney

(1), uncommon (0.1%-1%): hematuria.

(2). Frequency not reported: renal function damage.

12. Liver

Frequency not reported: Abnormal liver function test, elevated γ-glutamyl transferase (GGTP).

The above content only reflects the range of side effects in overseas registration countries and does not represent the approved use range in mainland China. Please do not make any treatment decisions based on this.