非那雄胺用法用量

It is a 4-nitrosteroid hormone compound and a specific type II 5α-reductase inhibitor. It can inhibit the conversion of peripheral testosterone into dihydrotestosterone and reduce the levels of dihydrotestosterone in tissues such as blood, prostate and skin. This product has no affinity for androgen receptors. Plasma drug concentrations are not directly related to plasma dihydrotestosterone concentrations. This product is indicated for the treatment and control of benign prostatic hyperplasia (BPH) and the prevention of urinary system events: reducing the risk of acute urinary retention; reducing the risk of transurethral resection of the prostate (TURP) and prostatectomy. This product can shrink the enlarged prostate, improve urine flow and relieve symptoms related to prostatic hyperplasia. Patients with prostatic hypertrophy are suitable for treatment with this product.

What is the dosage of Finasteride?

Orally administered to adults. BPH: 5 mg once a day. Male androgenetic alopecia: The recommended dose is 1 mg once a day. Dosage in renal insufficiency: There is no need to adjust the dose in patients with renal insufficiency but not undergoing dialysis. Dosage for the elderly: In patients over 70 years old, the elimination half-life is slightly prolonged and the clearance rate is reduced, but this has no practical clinical significance, so there is no need to reduce the dosage of the drug in the elderly.

Renal Impairment: No dosage adjustment is required in patients with renal impairment. In patients with chronic renal dysfunction (creatinine clearance in the range of 9-55ml/min), the AUC, Cmax and t1/2 after a single dose of 14C- are no different from healthy volunteers. Some metabolites that are normally excreted by the kidneys are excreted in the feces. Thus there is an increase in fecal excretion of metabolites and a corresponding decrease in urinary excretion. Hepatic insufficiency: No pharmacokinetic studies have been conducted in patients with hepatic insufficiency, but finasteride is mainly metabolized by the liver and should be used with caution in patients with hepatic insufficiency. Youth or children under 18 years of age: No pharmacokinetic studies have been conducted, so finasteride should be used with caution in these patients.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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