非那雄胺的治疗效果好不好？长期用会有哪些不良反应

Finasteride is a 4-azasteroid compound that is a specific inhibitor of type II 5a-reductase, an intracellular enzyme that metabolizes testosterone to the more potent form of dihydrotestosterone. This drug is regarded as a drug for the treatment of prostatic hyperplasia and male pattern baldness. Is the treatment effective? What are the adverse effects of long-term use?

The Prostate Cancer Prevention Trial (PCPT) study enrolled 18,882 men who received finasteride between 1993 and 1997 to evaluate the drug's effectiveness. After finding in 2003 that finasteride could reduce prostate cancer risk by 25%, researchers stopped the experiment.

Researchers linked patient information from the Prostate Cancer Prevention Trial (PCPT) study with Medicare information from 1999 to 2011, successfully matching information for 75% of patients in the PCPT study. Researchers found that 3,244 participants in the Prostate Cancer Prevention Trial (PCPT) were diagnosed with prostate cancer an average of 16 years later than controls. They also found that PCPT participants who took finasteride had a 21 percent lower risk of death from prostate cancer over 16 years. It can be seen from the above test results that finasteride can reduce the patient's risk of death, the drug can improve the patient's quality of life, and can have a positive effect on the patient's condition. The launch of this drug has brought new treatment options to many prostate cancer patients.

Finasteride adverse reactions

Adverse reactions of finasteride include: decreased libido, impotence, reduced ejaculation, breast tenderness or enlargement, allergic reactions, testicular pain, etc. If patients feel unwell during Finasteride treatment, they must go to the hospital for treatment, and a professional doctor will diagnose whether the patient needs to continue taking the medication. Patients are not allowed to use this medicine for treatment without authorization and must take it according to the doctor's instructions.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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