度他雄胺有什么副作用？

It is the first and only dual 5-alpha reductase inhibitor for the treatment of prostatic hyperplasia, which can improve urinary symptoms and reduce the risk of acute urinary retention episodes and related prostate surgery. Tamsulosin is an α-receptor blocker that can improve the symptoms of prostatic hyperplasia.

There are two types of 5α reductase in the human body, type I and type II. Type II is mainly found in the prostate, and type I is mainly distributed in the liver and skin. 5α reductase is an important reason for the continuous progression of benign prostatic hyperplasia. It can promote the conversion of testosterone in the patient's prostate to the more active dihydrotestosterone, thus leading to the proliferation of prostate cells and prostate hypertrophy. Therefore, the key to treating benign prostatic hyperplasia lies in inhibiting 5α-reductase. Dutasteride can simultaneously inhibit type I and type II 5α reductase. Through this "dual inhibition" mechanism, dutasteride can quickly and continuously reduce prostate volume, significantly improve lower urinary tract symptoms, reduce acute urinary retention and related prostate surgery risks, and bring lasting benefits to patients, especially the majority of patients with moderate and severe benign prostatic hyperplasia.

What are the side effects of Dutasteride?

Common side effects of dutasteride are: impotence (1% to 5%), decreased sexual desire (3.1%), decreased sexual desire (≤3%), male breast enlargement and pain (≤1%), difficulty in ejaculation (0.1% to 1.4%), reduced semen quantity, etc. If these side effects have bothered patients, or if these symptoms do not disappear completely after a period of time, they should seek medical help.

The more serious side effects are: difficulty breathing, throat tightening, swelling of the lips, tongue or face, skin rash, etc. Usually these side effects are rare, but if they occur, seek medical attention promptly.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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