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Vibegron is a β3 adrenoceptor agonist for overactive bladder (OAB). Patients need to master the correct method of taking Vibegron, understand potential side effects, and cooperate with daily treatment.

1. How to take Vibegroron

The efficacy of Vibegeron is closely related to the medication method. Patients must strictly follow the dosage and dosage specifications to avoid improper operation that affects the therapeutic effect.

1. Recommended dose and frequency

The standard adult dose is 75 mg orally once daily. Swallow the whole tablet and can take it with a meal or on an empty stomach. There are individual differences between patients, and the specific dosage needs to be followed by a doctor's advice. Elderly patients and those with mild to moderate hepatic and renal insufficiency do not need to adjust the dosage, but adverse reactions need to be closely monitored.

2. How to take it

Vibegroron needs to be swallowed whole and taken with at least a glass of water to avoid the tablets getting stuck in the esophagus. If you have difficulty swallowing, crush the tablets and mix with a tablespoon (about 15 mL) of applesauce. Take it immediately with warm water. Do not prepare or store it in advance.

3. Medication Precautions

If you miss a dose of Vibegeron, you should take it as soon as possible. If it is close to the next dose time, skip this time. Do not take double dosage of Vibegeron. It is contraindicated in patients who are allergic to Vibegroron, have severe urinary retention or have bladder outlet obstruction to avoid affecting their own health.

Digoxin, muscarinic antagonists and other drugs may have drug interactions with Vibegroron. You should inform your doctor in advance before taking the medication, and the doctor will guide you in your medication.

2. What side effects will Vibegroron cause?

Although Vibegroron is relatively safe, it may still cause adverse reactions. Patients need to understand common and serious side effects and master countermeasures.

1. Common side effects

Including headache, urinary tract infection, nasopharyngitis and upper respiratory tract infection, diarrhea and nausea, etc. Symptoms need to be treated accordingly.

Take headaches and nasopharyngitis as examples. When headache symptoms occur, they can be relieved by resting or taking over-the-counter analgesics (such as acetaminophen). When nasopharyngitis occurs, antihistamines or nasal sprays need to be used symptomatically, and patients should avoid contact with allergens.

2. Serious side effects

Including urinary retention, angioedema, etc. Symptoms of urinary retention include difficulty urinating and bladder distension and pain. The patient needs to immediately stop the medication, have a urinary catheter to relieve symptoms, and seek medical attention to evaluate bladder function.

Symptoms of angioedema include swelling of the face and throat, and difficulty breathing. The patient needs to stop taking the medication immediately and receive emergency treatment, and use epinephrine, glucocorticoids and other drugs to maintain a clear airway.

Regularly check liver and kidney function and electrocardiogram to prevent potential toxicity. Most side effects can be effectively controlled through early intervention. If patients experience severe reactions, they need to stop taking the drug immediately and seek medical treatment. Do not deal with it by yourself.

3. Daily treatment of overactive bladder

The treatment of overactive bladder requires a combination of drugs and lifestyle adjustments. Patients can improve their symptoms and improve their quality of life through comprehensive management.

1. Bladder training and pelvic floor muscle exercise

Patients need to urinate regularly, set to urinate every 2-3 hours, and gradually extend the interval to increase bladder capacity. You can perform appropriate exercises every day. Contract the pelvic floor muscles for 5 seconds and then relax. Repeat 10-15 times to strengthen urinary control ability.

2. Diet and drinking water management

Patients should limit irritating foods and reduce the intake of caffeine, alcohol, carbonated drinks and spicy foods to reduce bladder sensitivity. Drink water scientifically, control the daily water intake to 1.5-2 liters, drink in portions, and reduce drinking water 2 hours before going to bed.

Patients need to take Vibegroron strictly according to the doctor’s instructions, record changes in symptoms, such as the number of urgent urinations and frequency of nocturia, and provide regular follow-up feedback. For social anxiety or depression caused by frequent trips to the toilet, you can seek professional psychological counseling.